Orthomolecular medicine, which uses optimal doses of nutrients to maintain health and treat diseases, has gained increasing attention in recent years, especially for its role in supporting immune health. One of the most prominent examples is the use of Vitamin D3 to enhance immunity, particularly in the context of COVID-19. A recent review by Dr. Sunil Wimalawansa, who was one of the members of our 2024 International Expert Forum on Vitamin D (1), reviewed over 300 clinical trials, and concluded there is a causal relationship between vitamin D deficiency and SARS-CoV-2 Susceptibility, Complications, and Mortality (2).